Universidade Católica de Brasília;Massachusetts Institute of Technology
发明人:
Timothy Kuan-Ta Lu,Cesar De la Fuente Nunez,William Porto,Octavio Franco
申请号:
US16299641
公开号:
US20190279741A1
申请日:
2019.03.12
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed herein are methods of designing peptides having at least one property of interest, such as α-helical propensity, higher net charge, hydrophobicity, and/or hydrophobic moment. Also disclosed herein are novel artificially evolved peptides (e.g., antimicrobial peptides), which may be designed according to the methods described herein, and methods of use thereof.