An end effector and staple magazine assembly thereof, and surgical operation instrument the staple magazine assembly (1) comprises a staple cartridge (14), a staple pushing slider (12) and a cutting knife (11) the staple pushing slider (12) is slidably mounted on the staple cartridge (14) the cutting knife (11) is located in a cutting knife groove (141) of the staple cartridge (14) one end of the cutting knife (11) distal from a staple exiting surface of the staple cartridge (14) is pivotally connected to the staple pushing slider (12) via a pin shaft (13) an axial line of the pin shaft (13) is perpendicular to the cutting knife groove (141) the end surface of the cutting knife (11) facing a near side is a pushing surface pressing against the knife pushing rod (3) of a surgical operation instrument an elastic resetting member (15) is provided between the cutting knife (11) and the staple pushing slider (12) and the knife-edge portion of the cutting knife (11) is received in the cutting knife groove (141) of the staple cartridge (14) under an acting force of the elastic resetting member (15) when the cutting knife (11) is free of a pushing force of the knife pushing rod (3), and the cutting knife (11) rotates around the pin shaft (13) to be in a cutting state when acted upon by the pushing force of the knife pushing rod (3). The cutting knife (11) of the staple magazine assembly (1) is used only once, thus ensuring the sharpness of the knife-edge portion of the cutting knife when the surgical operation instrument is used in an operation, improving operation quality, and reducing medical risk.Linvention concerne un effecteur terminal et son ensemble chargeur dagrafes, ainsi quun instrument dopération chirurgicale lensemble chargeur dagrafes (1) comporte une cartouche dagrafes (14), un coulisseau de poussée dagrafes (12) et une lame de coupe (11) le coulisseau de poussée dagrafes (12) est monté de façon coulissante sur la cartouche dagrafes (14) la lame de coupe (11
