The object of present invention is to provide a reversal agent capable of reversing the anticoagulant effect of FXa inhibitor and a reversal method by using the same.The solution is a reversal agent, which is a reversal agent of the anticoagulant effect of oral anticoagulant, and is selected from one or two or more of group consisting of dry human blood coagulation factor antibody roundabout activity complex, dry human blood coagulation factor IX complex, and gene recombinant activity type factor VII.本發明之課題在於提供一種逆轉劑,其係將FXa抑制藥之抗凝固作用逆轉;及/或使用逆轉劑之逆轉方法。課題解決手段為一種逆轉劑,其係口服抗凝固藥的凝固作用之逆轉劑,係選自乾燥後的人類血液凝固因子抗體旁路活性複合體、乾燥後的人類血液凝固第IX因子複合體、及基因重組活性型第VII因子所構成之群中1或2種以上。
