James Donegan;Baoying Liu;Richard Nussenblatt;Lai Wei;Elazar Rabbani;Enzo Biochem, Inc.
发明人:
Nussenblatt, Richard,Liu, Baoying,Wei, Lai,Rabbani, Elazar,Donegan, James J.
申请号:
AU2014257219
公开号:
AU2014257219A1
申请日:
2014.04.22
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The disclosure relates to methods of identifying a compound that comprises an epitope that induces immune tolerance in a patient suffering from an autoimmune disease. The disclosure further relates to methods of treating an autoimmune disease by administering (i) a compound identified by the methods described herein, (ii) regulatory T-cells from the patient or a compatible donor, or (iii) a combination of regulatory T-cells and a compound identified by the methods described herein. The disclosure further relates to methods of treating age-related macular degeneration and uveitis.