SANIÈRE LAURENT RAYMOND MAURICE,HUCK JACQUES,DYKES GRAEME JAMES,SCHMITT BENOÎT ANTOINE,BLANC JAVIER,BUTLER ANNA SARA,BEAUMONT STÉPHANE NICOLAS ALAIN,BONNATERRE FLORENCE MARIE-EMILIE
申请号:
IN201627003446
公开号:
IN201627003446A
申请日:
2016.02.01
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention discloses compounds according to Formula (I): wherein R R R R L and X are as defined herein. The present invention relates to compounds methods for their production pharmaceutical compositions comprising the same and their use in the prophylaxis and/or treatment of inflammatory conditions type 2 diabetes neurological and/or neurodegenerative diseases autoimmune diseases proliferative diseases (in particular metastatic diseases and/or cancer) abnormal angiogenesis associated diseases degradation of cartilage and/or disruption of cartilage homeostasis in particular in the prophylaxis and/or treatment of cancer. The present invention also discloses methods of treatment using the same compounds for the prophylaxis and/or treatment of said diseases by administering the compound of the invention.