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POLYPEPTIDE FÜR DAS SPEZIFISCHE TARGETING GEGEN OTX2-TARGETZELLEN
专利权人:
ECOLE NORMALE SUPERIEURE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人:
PROCHIANTZ, ALAIN,DI NARDO, ARIEL,BEURDELEY, MARINE,HENSCH, TAKAO K.
申请号:
EP10704386.1
公开号:
EP2387579B1
申请日:
2010.01.19
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The invention relates to polypeptides which enable the specific targeting of a molecule of interest to homeoprotein Otx2 target cells. These polypeptides are defined by the general sequence: B1B2X1B3B4X2B5X3X4X5X6B6X7X8X9 (SEQ ID NO: 1), in which: B1, B2, B3, B4, B5 and B6are independently arginine or lysine; X1 and X8 are independently asparagine or glutamine; X2 is aspartic acid or glutamic acid; X3, X4 and X6 are independently threonine or serine; X5 is phenylalanine, tyrosine or tryptophan; X7 represents alanine or glycine; X9 is leucine, isoleucine or valine.
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