Thomas A. Davis,Khairul Anam,Eric A. Elster,Douglas K. Tadaki
申请号：
US14210701
公开号：
US20150258144A1
申请日:
2014.03.14
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A method inducing chimerism and allograft tolerance by co-infusion of stein/progenitor-like cells and donor cells, wherein the donor cells can be bone marrow cells. The method also comprises the conditioning comprising depletion of CD4+ and CD8+ T-cells and administration of low doses of anti-neoplastic drugs. The inventive method comprises an aspect wherein allograft tolerance is induced without systemically suppressing the immune system.
