The present invention pertains to a pharmaceutical composition for the prevention or treatment of kidney disease, an inflammation inhibitor for the kidneys, an inflammatory cell death inhibitor for the kidneys, or a food for the prevention or improvement of kidney disease, that include D-serine or a derivative thereof. In addition, the present invention pertains to the use of D-serine or a derivative thereof, for the production of a pharmaceutical composition for the prevention or treatment of kidney disease.本發明係關於一種包含D-絲胺酸或其衍生物之腎臟病之預防或治療用之醫藥組合物、腎臟之炎症抑制劑、腎臟之炎症性細胞死亡抑制劑、或腎臟病之預防用或改善用食品。又,本發明係關於一種用以製造腎臟病之預防或治療用之醫藥組合物之D-絲胺酸或其衍生物之用途。