Keith Bauer,Thomas W. Myers,Fred Reichert,Joseph San Filippo,Rachel Shahinian,Shawn Suko
申请号：
US15462026
公开号：
US10597644B2
申请日:
2017.03.17
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Disclosed are DNA polymerases having increased reverse transcriptase efficiency, mismatch tolerance, extension rate and/or tolerance of RT and polymerase inhibitors relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases.
