Luis BRITO,Stephanie Kay DODD,Derek OHAGAN,Manmohan SINGH
申请号:
US15126508
公开号:
US20170080084A1
申请日:
2015.03.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Oil-in-water emulsions with small droplet sizes can be formed without requiring either microfluidisation or heating to cause phase inversion, but rather by simple mixing of a pre-mixed composition of oil and a surfactant component comprising at least one surfactant component with aqueous material. The HLB value of the surfactant component can be selected to give a composition which, on mixing with a volume excess of aqueous material, spontaneously forms an oil in water emulsion with submicron oil droplets having a diameter <250 nm, suitable for filter sterilisation. Droplet diameters of <40 nm can also be achieved.