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DÉRIVÉS AMINO-TRIAZINE ET COMPOSITION PHARMACEUTIQUE CONTENANT LESDITS DÉRIVÉS
专利权人:
Shionogi & Co.; Ltd.
发明人:
申请号:
EP14810134.8
公开号:
EP3009432A1
申请日:
2014.06.13
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic activity.A compound of Formula (I):wherein Ra and Rb, and Rd and Re are taken together to form oxo or the like; R4a and R4b are hydrogen or the like; n is 1 or the like; R2 is aryl or the like; s and s' is 0 or the like;R9 and R9' are halogen or the like; R20a and R20b are hydrogen, alkyl or the like; u is 1 to 4; R13 is hydrogen or the like,or its pharmaceutically acceptable salt.
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