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2-氟-N-甲基-4-〔7-(喹啉-6-基-甲基)-咪唑并〔1,2-b〕〔1,2,4〕三-2-基〕苯甲醯胺之鹽類及其相關製備方法
专利权人:
INCYTE CORPORATION
发明人:
WENG, LINGKAI,QIAO, LEI,ZHOU, JIACHENG,LIU, PINGLI,PAN, YONGCHUN
申请号:
TW98116761
公开号:
TWI472529B
申请日:
2009.05.20
申请国别(地区):
TW
年份:
2015
代理人:
摘要:
The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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