Claudine KIEDA;Yves Claude NICOLAU;Jean-Marie LEHN
发明人:
Yves Claude NICOLAU,Jean-Marie LEHN,Claudine KIEDA
申请号:
US13033363
公开号:
US20120003327A1
申请日:
2011.02.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Inositol trisphosphate (ITPP) causes normalization of tumor vasculature and is a particularly effective cancer therapy when a second chemotherapeutic agent is administered following partial vascularization. ITPP also treats, alone or in combination, multi-drug resistant cancers. ITPP can also be used to reduce the amount of a second chemotherapeutic drug required for anticancer activity. In addition, ITPP enhances immune response and treats hyperproliferative disorders.