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Her2 binding peptides labelled with a 18f - containing organosilicon compound
专利权人:
GE HEALTHCARE LIMITED
发明人:
HISCOCK DUNCAN,INDREVOLL BARD,GLASER MATTHIAS EBERHARD,BHALLA RAJIV,WILSON ANTHONY,IVESON PETER
申请号:
NZ61232711
公开号:
NZ612327A
申请日:
2011.12.19
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed is an imaging agent composition that comprises an isolated polypeptide comprising SEQ. ID No. 1 or SEQ. ID. No 2, conjugated with 18F-SiFA via an isotopic fluorine exchange chemistry wherein the isolated polypeptide binds specifically to HER2 or variants thereof wherein the sequences are as defined in the specification. Also disclosed are methods of making such an imagining agent.
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