Allan, Christian B.,Oliver, Cynthia N.,Chang, Stephen
申请号：
AU2011226771
公开号：
AU2011226771B2
申请日:
2011.09.20
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2011226771B220121004.pdf#####STABILIZED ANTI-RESPIRATORY SYNCYTIAL VIRUS (RSV) ANTIBODY FORMULATIONS Abstract The present invention provides liquid formulations of antibodies or fragments s thereof that immunospecifcally bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of the antibodies or antibody fragments, even during long periods of storage. In particular, the present invention provides liquid formulations of antibodies or fragments thereof that immunospecifcally bind to a RSV antigen, which 10 formulations are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides methods of preventing, treating or ameliorating one or more symptoms associated with RSV infection utilizing the liquid formulations of the present invention.
