Universität für Bodenkultur Wien;Universität Wien;Veterinärmedizinische Universität Wien
发明人:
申请号：
EP18172615.9
公开号：
EP3569698A1
申请日:
2018.05.16
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The present invention provides a method for obtaining a fraction of a fetal cell culture supernatant, comprising the steps of obtaining a cell-containing sample of tissue (such as cartilage) or (cord-)blood or bone marrow from a non-human mammalian fetus, culturing the sample in a liquid cell culture medium, thereby obtaining a cell culture with a liquid supernatant, and isolating a fraction from the supernatant. Furthermore, a fraction obtainable by this method is provided. A pharmaceutical composition comprising this fraction is also provided, preferably for use in therapy, such as for use in a prevention or treatment of osteoarthritis, arthritis, tendinitis, tendinopathy, cartilage injury, tendon injury, rheumatoid arthritis, discospondylitis, meniscus injury, desmitis, desmopathy, intervertebral disc injuries, degenerative disease of intervertebral discs, reperfusion injury, wounds or inflammatory disease.
