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controlled release composition for producing a sustained-release preparation containing the udenafil
专利权人:
DONG-APHARM.CO.; LTD
发明人:
YOO, MOO-HI,CHA, BONG-JIN,KIM, JEONG-HOON,JANG, SUN-WOO,HAN, SANG-DUG
申请号:
MA33942
公开号:
MA33022B1
申请日:
2011.06.14
申请国别(地区):
MA
年份:
2012
代理人:
摘要:
يتعلق الاختراع بتركيبة ذات إفراز متحكم فيه لإنتاج تحضير بإفراز مطول يحتوي على "الإودينافيل.بشكل خاص أكثر، يتعلق الاختراع بتركيبة ذات إفراز متحكم فيه لإنتاج تحضير بإفراز مطول يحتوي على "الإودينافيل، تحتوي هذه التركيبة على أ) الأودينافيل وملح مقبول صيدليا،ب)معدِّلthe present invention relates to a controlled release composition for producing a sustained-release preparation containing of udenafil.more particularly, the present invention relates to a controlled release composition for producing a sustained-release preparation containing the udenafil, the composition containing (a) a pharmaceutically acceptable salt of the udenafil and (b) a modulator of solubil m, (c) and (d) an adsorbent, and a hydrophilic polymer.controlled release composition for producing a sustained-release preparation containing udenafil according to the present invention, the release of drugs constantly regardless of the level of ph in the gastro intestinal tract, and the length of control freely. drug treated within the range of 3 to 24 hours.and reduces the variability of the effects of drugs among individuals.in addition, the composition of the present invention can be produced in an extended release preparation which has an optimum condition for expressing the effect of medication in the treatment of diseases such as pulmonary arterial hypertension, portal hypertension, liver benign prostatic hyperplasia, and, like,that can be dealt with by udenafil and require the administration of drugs over a long period of time.the composition of the present invention can regulate the release of drugs as a function of the time required for absorption thereof when the medication is administered to a living body, and can be used as beneficial in the prevention and t treatment of erectile dysfunction.La présente invention concerne une composition à libération contrôlée pour produire une préparation à libération prolongée contenant de l'udénafil. Plus particulièrement, la présente invention concerne une compo
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