An X-ray diagnostic apparatus according to an embodiment includes a support frame and processing circuitry. The support frame supports an X-ray generator and an X-ray detector. The processing circuitry is configured to, when rotational acquisitions are performed multiple times after a contrast agent is injected one time, previously set a generation condition of an X-ray that is generated by the X-ray generator for each of the rotational acquisitions, the rotational acquisitions being performed while the support frame is rotated around a subject.
