SHENZHEN IN VIVO BIOMEDICINE TECHNOLOGY LIMITED COMPANY
发明人:
Yunxin Lai,Simiao Lin,Yao Yao,Peng Li
申请号：
NZ72207615
公开号：
NZ722076A
申请日:
2015.08.07
申请国别(地区):
NZ
年份:
2019
代理人:
摘要：
The present invention relates to a chimeric antigen receptor, comprising an extracellular domain capable of binding to an antigen, a transmembrane domain and an intracellular domain； a nucleic acid encoding the same and a cell expressing the same, and their use in manufacturing drugs for treating tumors. The chimeric antigen receptor of the present invention is characterized by its intracellular domain including at least Toll-like receptor 1 being encoded by the nucleotide sequence of SEQ ID NO: 11 and/or Toll-like receptor 2 intracellular domain being encoded by the nucleotide sequence of SED ID NO: 12.
