The invention concerns a probe (10, 20) for laser treatment of uneven structures or deformations of a body. The laser devices (16, 20, 22) are arranged on a partially domed surface (18, 24) in order to cover the uneven structures. The doming has a smooth surface treatment, which facilitates sweeping in the probe over uneven structures. The probe insludes a handgrip (12), covered with a material that increases the adhesion to a hand. In particular, the probe is intended for treatment of neurological and rheumatic desease conditions.