A method for determining a candidate lesion region in a digital ultrasound medical image of anatomical tissue. The method includes the steps of: accessing the digital ultrasound medical image of anatomical tissue applying an anisotropic diffusion filter to the ultrasound image to generate a filtered ultrasound image performing a normalized cut operation on the filtered ultrasound image to partition the filtered ultrasound image into a plurality of regions and selecting, from the plurality of regions, at least one region as a candidate lesion region.