compound, pharmaceutical composition, and methods for treating cancer, reducing tumor size, treating hgf-mediated disorders, and reducing metastasis in a tumor in a patient
BRIAN ALBRECHT,DAVID BAUER,STEVEN BELLON,CHRISTIANE BODE,SHON BOOKER,ALESSANDRO BOEZIO,DEBORAH CHOQUETTE,DERIN D'AMICO,JEAN-CHRISTOPHE HARMANGE,SATOKO HIRAI,RANDALL HUNGATE,TAE-SEONG KIM,RICHARD LEWIS
申请号：
BRPI0714387
公开号：
BRPI0714387A2
申请日:
2007.07.13
申请国别(地区):
BR
年份:
2013
代理人:
摘要：
COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE OF A COMPOUND. The selected compounds are effective for the prophylaxis and treatment of diseases such as HGF-mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for the prophylaxis and treatment of diseases and other diseases or conditions involving cancer and others. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.COMPOSTO, COMPOSIÇçO FARMACÊUTICA, E, USO DE UM COMPOSTO. Os compostos selecionados são eficazes para as profilaxias e tratamento de doenças, tais como doenças mediadas por HGF. A invenção abrange novos compostos, análogos, pró-drogas e sais farmaceuticamente aceitáveis destes, composições farmacêuticas e métodos para profilaxia e tratamento de doenças e outras enfermidades ou condições envolvendo, câncer e outros. A invenção objeto também diz respeito a processos para fabricar tais compostos assim como aos intermediários úteis en tais processos.
