A guide wire may include a core member and an outer coil disposed about the core member. The outer coil may be longitudinally movable relative to the core member between retracted and advanced positions. An anchor member may include an elongate wire having proximal and distal ends attached to the distal ends of the outer coil and the core member, respectively. In response to longitudinal movement of the outer coil relative to the core member, the anchor member may be movable between delivery and deployed configurations. A retaining mechanism may include a tubular member removably positionable about the core member and in abutting contact with a proximal end of the outer coil. The retaining mechanism may be engageable with the core member to inhibit longitudinal movement of the outer coil proximally relative to the core member.