Joseph M. Pastore,Jeffrey Ross,Tamara Colette Baynham,Rodney W. Salo,Andrew P. Kramer,Julio C. Spinelli
申请号：
US12830534
公开号：
US08538520B2
申请日:
2010.07.06
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A gene regulatory system detects ischemia events and is capable of delivering a biologic therapy in response to the detection of an ischemic event or the reception of a command. The biologic therapy protects the heart from ischemic damage by regulating the expression of an exogenously introduced gene product. In one embodiment, the gene regulatory system includes an implantable system that emits at least one gene regulatory signal in response to the detection of the ischemic event or the reception of the command. The gene regulatory signal directly or indirectly regulates gene expression of the gene product.
