A lyophilizing and/or sterilizing machine comprises a treatment chamber, a plurality of loading planes having at least one loading surface, disposed inside the treatment chamber, one overlapping the other and positionable in a desired and known manner by means of vertical tie-rods. The lyophilizing and/or sterilizing machine also comprises a movement apparatus to move containers, the content of which is to be treated in the treatment chamber. The movement apparatus comprises at least one loading/unloading device mobile on horizontal guides comprising at least one internal horizontal guide independent and autonomous from the loading planes and located in correspondence to a lateral portion of the loading planes and between the loading surface and the vertical tie-rods.
