THE GOVERMENT OF THE UNITED STATES; AS REPRESENTED BY THE SECRETARY OF THE ARMY
发明人:
Sheetij Dutta,John David Haynes,Adrian Batchelor,Michael Foley
申请号：
US15035914
公开号：
US20160279221A1
申请日:
2014.11.11
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Disclosed are AMA-1 immunogenic peptides and epitopes, nucleotide sequences encoding the peptides and epitopes, compositions, and vaccines including the peptides and/or epitopes. Antibodies that specifically bind to AMA-1 and the AMA-1 epitopes and immunogenic peptides disclosed herein are also provided. The disclosure provides for expression vectors, host cells, and methods for making the polypeptides and antibodies. Also provided are methods of treatment, prevention, vaccination, and/or immunization of a subject against malaria and the clinical indications associated with malaria.
