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Antimicrobial peptide, branched forms thereof and their use in the treatment of bacteria infections
专利权人:
Alessandro Pini
发明人:
Alessandro Pini,Chiara Falciani,Luisa Bracci
申请号:
US13811039
公开号:
US08921308B2
申请日:
2011.07.11
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The instant invention refers to an antibacterial peptide with all amino acids in D-configuration, possessing strong antimicrobial activity against Gram-negative and Gram-positive bacteria and Candida strains. The peptide can be in linear form multimerised on a skeleton of polyacrylamide, of dextrane units or on a skeleton of ethylene glycol units. The peptide is resistant proteolysis especially when synthesized in the tetra-branched form where identical peptide sequences are linked together by an appropriate molecular scaffold.
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