The invention relates to a device and to a method for continuous virus inactivation. The device for continuous virus inactivation in a product flow comprises a pipe or hose (1) having an inlet (4) and having an outlet (5) each connected to a product flow line (8) for conducting the product flow wherein the pipe or the hose (1) is curved and/or is helically wound with a number of n windings about a winding axis (h) and has one or more direction changes and/or kinks (2) of the winding axis (h) having an angle (a) of 45° to 180° for changing the effective direction of the normal of the centrifugal force and wherein the device is characterized by a Dean number > 0 and a torsion parameter > 0.