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שיטה והרכבים לאימונו–תרפיה תאית
专利权人:
FRED HUTCHINSON CANCER RESEARCH CENTER
发明人:
申请号:
IL22860313
公开号:
IL228603D0
申请日:
2013.09.29
申请国别(地区):
IL
年份:
2013
代理人:
摘要:
The present invention provides methods and compositions to confer and/or augment immune responses mediated by cellular immunotherapy, such as by adoptively transferring genetically modified tumor specific CD8+ T cells in the presence of tumor-specific, subset specific genetically modified CD4+ T cells, wherein the CD4+ T cells confer and/or augment a CD8+ T cells ability to sustain anti-tumor reactivity and increase and/or maximize tumor-specific proliferation of the tumor-specific CD8+ T cells of interest. Pharmaceutical formulations produced by the method, and methods of using the same, are also described.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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