ニューロン生存因子およびその使用

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专利权人:

アンスティテュ、ナショナル、ド、ラ、サント、エ、ド、ラ、ルシェルシュ、メディカル(アンセルム)

发明人:

ティエリー、ルベイラル,ジョゼ‐アラン、サエル,セリーヌ、ジェラール,オリビエ、ポシュ

申请号：

JP2010510812

公开号：

JP5671678B2

申请日:

2008.06.05

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

The present invention concerns a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a compound selected in the group comprising (i) a polypeptide comprising an amino acid sequence selected in the group comprising the amino acid sequence of the short isoform in Homo sapiens of the RdCVF2 gene (SEQ ID NO:1), orthologs, derivatives and fragments thereof, (ii) a polynucleotide coding for said polypeptide, (iii) a vector comprising said polynucleotide, and (iv) a host cell genetically engineered expressing said polypeptide the use of such a composition for the manufacture of a medicament for treating and/or preventing a neurodegenerative disorder in a subject and a method of testing a subject thought to have or be predisposed to having a neurodegenerative disorder.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/