Anatomy mannequins, models and medical simulation systems described herein may facilitate various medical procedure training by rendering a realistic passive haptic touch when the end user manipulates the anatomy model with a handheld tool. An anatomy tissue model may comprise at least one fabric layer arranged over at least one foam layer to replicate the low-friction, elasticity and hardness of a living body anatomy tissue, such as the vagina wall, without requiring the use of lubricant in the medical simulation training procedure. The anatomy tissue model may be attached as an insert to a body structure model. A diversity of anatomy tissue models may be adapted with different fabric layer and/or foam layer designs, each design corresponding to a different haptic touch, so they can be interchanged in a medical training simulator system to realistically replicate different medical training scenarios.