HWANG, YONG YOUN,황용연,CHOI, WON JAE,최원재,KIM, JAE SUN,김재선,YOUN, WON NO,윤원노,PARK, YEO JIN,박여진,OH, JOON GYO,오준교,IM, JONG SEOB,임종섭
申请号：
KR1020120053447
公开号：
KR1020120130073A
申请日:
2012.05.21
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A rivastigmine containing patch is provided to enhance stability and to express optimal emission pattern.CONSTITUTION: A rivastigmine containing patch comprises rivastigmine free base, a copolymer including butyl methacrylate and methylmethacrylate and drug adhesive layer manufactured by using adhesive, and double layer of skin adhesive layer which includes silicon gluing agent. As adhesive of the drug adhesive layer, 58-66 parts by weight of 2- ethylhexylacrylat, 28-36 parts by weight of random copolymer and a random copolymer of 4-8 parts by weight of acrylic acid are used. The DURO-TAK&trade 87-235A (henkel corp) is used as the adhesive of the drug adhesive layer. The copolymer of the methylmethacrylate and butyl methacrylate is the random copolymer of the methylmethacrylate and butyl methacrylate, and has the weight-average molecular weight of 130,000-170,000 g/mol.COPYRIGHT KIPO 2013본 발명은 보관 안정성이 향상되고, 적절한 방출성을 가지는 리바스티그민 함유 패취에 관한 것이다.
