BRYHN, MORTEN,HOLMEIDE, ANNE KRISTIN,ROSMAN, JENNY
申请号：
EP07825558
公开号：
EP2094640A4
申请日:
2007.11.01
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Omega-3 lipid compounds of the general formula (I): wherein R1 and R2 are the same or different and may be selected from a group of substituents consisting of hydrogen, a hydroxy group, an alkyl group, a halogen atom, an alkoxy group, an acyloxy group, an acyl group, an alkenyl group, an alkynyl group, an aryl group, an alkylthio group, an alkoxycarbonyl group, a carboxy group, an alkylsulfinyl group, an alkylsulfonyl group, an amino group, and an alkylamino group； X represents a carboxylic acid or a derivative thereof, a carboxylate, a carboxylic anhydride or a carboxamide； and Y is a C6 to C22 alkene with two or more double bonds, having E and/or Z configuration, are disclosed. Also disclosed are pharmaceutical compositions and lipid compositions comprising such compounds, and to such compounds for use as medicaments in particular for the treatment of cardiovascular and metabolic diseases.
