ZAUDERER, MAURICE,YOSHIDA, MASARU,YAMAMOTO, KOJI,SMITH, ERNEST S.
申请号:
CA2899344
公开号:
CA2899344A1
申请日:
2014.01.31
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Methods for increasing immunoglobulin A (IgA) levels in a subject having a deficiency thereof are provided herein by administering to the subject an agent that inhibits CXCL13 activity, such as an anti-CXCL13 or an anti-CXCR5 antibody. Further provided are methods for treating an inflammatory disorder in a subject deficient for IgA by administering to the subject an agent that inhibits CXCL13 activity.