Novel antibodies inhibiting c-Met dimerization, and uses thereof

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专利权人:

Pierre Fabre Medicament

发明人:

Goetsch, Liliane

申请号：

AU2008274171

公开号：

AU2008274171B2

申请日:

2008.07.10

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The present inventions relates to a process for the selection of anti c-Met antibodiescapable to inhibit both ligand-dependent and ligand-independent activationof c-Met. More particularly, said process is based on the inhibition of the c-Metdimerization. In another aspect, the present invention concerns such antibodiesand compositions comprising such antibodies for the preparation of a medicamentto treat cancer. Diagnosis process and kits are also part of the invention.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/