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ANTI-CANCER EFFECTS OF PROTEASOME INHIBITORS IN COMBINATION WITH GLUCOCORTICOIDS, ARSENIC CONTAINING COMPOUNDS, AND ASCORBIC ACID
专利权人:
发明人:
James R. BERENSON
申请号:
US15317690
公开号:
US20170224730A1
申请日:
2015.06.10
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides methods of treatment for hematological malignancies involving synergistic combination of a proteasome inhibitor, a glucocorticoid, an arsenic-containing compound, and ascorbic acid or a derivative thereof provide an unexpected efficacy in the treatment for hematological disorders. The hematological disorders treated by the current invention include multiple myeloma, and may also include hematological disorders that are refractory to prior cancer treatments, or relapsed hematologic disorders.
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