שימוש בתכשירים המכילים נגזרות של הקסיטול לטיפול בסרטן

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专利权人:

JEFFREY BACHA;SANDRA DUNN;DENNIS BROWN

发明人:

申请号：

IL23372214

公开号：

IL233722D0

申请日:

2014.07.20

申请国别(地区):

IL

年份:

2014

代理人:

摘要：

The use of dianhydrogalactitol provides a novel therapeutic modality for the treatment of glioblastoma multiforme and medulloblastoma. Dianhydrogalactitol acts as an alkylating agent on DNA that creates N7 methylation. Dianhydrogalactitol is effective in suppressing the growth of cancer stem cells and is active against tumors that are refractory to temozolomide； the drug acts independently of the MGMT repair mechanism.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/