The present invention is directed to novel substituted aminocyclohexanes which are inhibitors of the dipeptidyl peptidase-IV enzyme (DPP-IV inhibitors) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.La présente invention a trait à de nouveaux aminocyclohexanes substitués qui sont inhibiteurs de lenzyme dipeptidyle peptidase-IV (inhibiteurs DPP-IV) et qui sont utiles dans le traitement ou la prévention de maladies dans lesquelles lenzyme dipeptidyle peptidase-IV est impliquée, telles que le diabète et en particulier le diabète de type 2. Linvention a également trait à des compositions pharmaceutiques comportant ces composés et lutilisation de ces composés et compositions dans la prévention ou le traitement de telles maladies dans lesquelles lenzyme dipeptidyle peptidase-IV est impliquée.
