Cavity induced allosteric modification of intermolecular interactions and methods of identifying compounds that effect the same

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专利权人:

Mark I. Greene;Ramachandran Murali

发明人:

Ramachandran Murali,Mark I. Greene

申请号：

US13194832

公开号：

US08785419B2

申请日:

2011.07.29

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Method of identifying compounds that modulate intermolecular interactions between a target protein and a modifier are disclosed. Pharmaceutical composition comprising compounds that inhibit intermolecular interactions between a target protein and a modifier are disclosed. Methods of treating individual suffering from inflammatory conditions, undesirable immune responses, immunological conditions and bacterial infections are disclosed.

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