The present invention relates to a complex comprising polmacoxib andtramadol. The present invention relates to a pharmaceutical composition and amedicine or an analgesic, all of which contain two types of active ingredientsofpolmacoxib and tramadol, and, more specifically, to effects and uses of theactiveingredients in a medicine or an analgesic for the treatment of moderate acuteandchronic pain caused by inflammatory and multiple factors.