PROBLEM TO BE SOLVED: To provide novel active agents for counteracting the deficiencies in tissue renewal of the skin or of the hair, in particular for reducing thinning of the epidermis, improving the surface appearance of the skin, correcting wrinkles, slowing down and/or inhibiting hair loss, or slowing down and/or inhibiting whitening of the hair.SOLUTION: The present invention relates to active agents comprising dedifferentiated plant cells of a plant of the Rosa sp, genus, or of an extract or a lyophilisate of the cells. The present invention also relates to rose dedifferentiated cells, in particular Lancome rose dedifferentiated cells.SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】皮膚又は毛の組織再生の不足に対抗する為の、特には表皮が薄くなることを減少し、皮膚の表面外観を改善し、しわを消し、毛の喪失を遅くし及び/又は抑制し、又は毛の白化を遅くし及び/又は抑制する為の新規活性剤を化粧的に使用する方法の提供。【解決手段】Rosa sp.属の植物の脱分化植物細胞又は該細胞の抽出物若しくは凍結乾燥物からなる活性剤。本発明はまた、バラ脱分化細胞、特にはLancomeバラ脱分化細胞に関する。【選択図】なし