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COMPOSITIONS DESTINES A LA THERAPIE PAR OXYBUTYNINE TRANSDERMIQUE
专利权人:
LLC;Allergan Sales
发明人:
申请号:
EP19208494.5
公开号:
EP3659562A1
申请日:
2003.10.31
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention provides compositions and methods for administering oxybutynin while minimizing the incidence and or severity of adverse drug experiences associated with oxybutynin therapy. In one aspect, these compositions and methods provide a lower plasma concentration of oxybutynin metabolites, such as N-desethyloxybutynin, which is presumed to be contributing at least in part to some of the adverse drug experiences, while maintaining sufficient oxybutynin plasma concentration to benefit a subject with oxybutynin therapy. The invention also provides isomers of oxybutynin and its metabolites that meet these characteristics of minimized incidence and/or severity of adverse drug experiences, and maintenance of beneficial and effective therapy for overactive bladder. In some aspects, the composition may be presented in the form of an unoccluded or free from topically administered gel.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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