PROBLEM TO BE SOLVED: To provide an immunonutritional composition for inhibiting damage to the immune function during anti-cancer treatment, and achieving the further satisfactory efficacy of treatment.SOLUTION: The invention provides an immunonutritional composition comprising an immuno-enhancing agent and a pharmaceutically acceptable carrier. The immuno-enhancing agent can preserve the innate immune function, the adaptive immune function, and the normal physiology of immune cells. The immuno-enhancing agent contains glutamine, arginine, or citrulline. The preservation of the immune functions and normal physiology results in a better tolerance and increased efficacy of the anti-cancer therapy and transient augmentation or enhancement of immunocompetence of the immune cell. The immunonutritional composition comprises a substance selected from a probiotic, a nucleic acid, an uric acid, carotenoid, a branched chain amino acid, theanine, cysteine, threonine, vitamin E, EPA, DHA, Lactoferrin protein, a protein source selected from whey, soybean, and casein, and the like.【課題】抗癌療法の間の免疫機能の損傷を阻止し、治療のより良好な有効性を達成するための免疫栄養組成物の提供。【解決手段】免疫増強剤及び薬学的に許容できる担体を含み、前記免疫増強剤が、前記免疫細胞の自然免疫機能及び適応免疫機能並びに正常な生理を保存することができ、前記免疫増強剤が、グルタミン、アルギニン、又はシトルリンを含み、前記免疫機能及び正常な生理の前記保存の結果、前記抗癌治療のより良好な耐性及び有効性の増加、並びに前記免疫細胞の免疫能の一過性の増大又は増強をもたらす免疫栄養組成物。さらにプロバイオティクス、核酸、尿酸、カロテノイド、分枝鎖アミノ酸、テアニン、システイン、スレオニン、ビタミンE、EPA、DHA、ラクトフェリンタンパク質、乳清、大豆及びカゼインから選択されるタンパク質源等から選択される物質を含む免疫栄養組成物。【選択図】なし