MORISSEAU, SEBASTIEN DANIEL,TEPPAZ, GERALDINE,JACQUES, YANNICK LAURENT JOSEPH,ROBERT, BRUNO GILBERT MARC,DE MARTYNOFF, GUY LUC MICHEL,BECHARD, DAVID
申请号:
CA2840113
公开号:
CA2840113A1
申请日:
2012.06.22
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15Ra or derivatives thereof and uses thereof.