LI CHIANG J,LI YOUZHI,GAO YUAN,WANG YUXIN,HUANG JANET,ROGOFF HARRY
申请号:
IN201727046364
公开号:
IN201727046364A
申请日:
2017.12.22
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
ABSTRACT COMPOSITIONS COMPRISING A CANCER STEMNESS INHIBITOR AND AN IMMUNOTHERAPEUTIC AGENT FOR USE IN TREATING CANCER Disclosed herein are methods for use in treating cancer comprising administering at least one cancer sternness inhibitor, for example, at least one STAT3 pathway inhibitor such as 2-acetylnaphtho 2, 3 -b furan-4, 9- dione, in order to sensitize or resensitive a cancer that is naive, resistant, or/and refractory to at least one immunotherapeutic agent, such as at least one immune checkpoint modulator.