A method of conditioning a living body of a patient to associate the unconditioned stimulus (US) of decreased sympathetic nerve activity SNA) with the conditioned stimulus (CS) of a representation of an offending agent to cease or reduce defensive reactions or symptoms. The US involves non-invasive, transcutaneous sensory stimulation of the sympathetic ganglia, which is paired with the CS of digital audio representations of offending substances to modify pathologically conditioned. reflexes of various systems involved. in a reaction. In addition, a patient's allergies or sensitivities are treated by using digital representations, preferably provided via a computer, to represent the actual substances in order to engage the multimodal functioning of the brain. Sensory stimulation is used in conjunction with the digital audio signals to condition the body to respond more appropriately to the substance.