To provide compositions comprising semifluorinated compounds, and medicaments for topical administration to an eye, for treatment of dry eye disease and/or meibomian gland dysfunction and any symptoms or conditions associated with these conditions.SOLUTION: The invention provides: a lubricant of an eye surface comprising CF(CF)(CH)CHand CF-(CF)-CH(CH)-(CH)-CH; and a composition comprising the lubricant.SELECTED DRAWING: None【課題】ドライアイ疾患および/またはマイボーム腺機能不全ならびにそれらの症候に関連する任意の症候または症状を処置するための、半フッ素化化合物を含む組成物、および眼への局所投与用の医薬品の提供。【解決手段】CF3(CF2)5(CH2)7CH3とCF3-(CF2)5-CH(CH3)-(CH2)5-CH3とを含む眼表面の潤滑剤、および当該潤滑剤を含む組成物。【選択図】なし