Provided are a sodium hydroxysafflor yellow A compound of formula I and the production method and pharmaceutical use thereof. Sodium hydroxysafflor yellow A having a purity above 98.5% is obtained through extraction transferring to a sodium salt separation and purification using a natural herb safflower as raw material. Sodium hydroxysafflor yellow A is safer more effective and more stable than hydroxysafflor yellow A when being applied to the treatment of blood circulation disorders such as preventing platelet aggregation coronary heart disease angina and acute cerebral ischemia and has good water solubility and tolerance to the human body.
