MURUGESAN, Natesan,GLUNZ, Peter W.,BODAS, Mandar Shrikrishna,YADAV, Navnath Dnyanoba,ALLA, Venu
申请号:
ES17728029
公开号:
ES2781309T3
申请日:
2017.05.26
申请国别(地区):
ES
年份:
2020
代理人:
摘要:
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.