Administration of an Anti-Interleukin 12/23 Antibody for Treatment of Autoimmune Disease

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专利权人:

Staley Brod

发明人:

Staley Brod

申请号：

US14525951

公开号：

US20160115227A1

申请日:

2014.10.28

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention provides a method for treating or delaying the onset of an autoimmune condition in a human subject. An effective oral dose of ustekinumab is administered to the subject. Oral administration of ustekinumab also is useful in a method of decreasing innate inflammatory cytokines, such as IL-1β and TNF-α, Th1-like cytokines IL-2 and IFN-γ, IL-17 (Teff), IL-12p70, and increasing Th2-like counter-regulatory cytokine IL-13 in a subject.

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